Back in the 90s, I had a cartoon idea I called 'VR for Dogs' - the idea would be to put a dog in a virtual environment that would allow them to go for a run using an omnidirectional treadmill surrounded by a dome that would display the virtual environment - if the VR was convincing enough to a dog, it should work wonders on humans.
So, here it comes - this version uses a harness - the Virtuix Omni:
http://www.virtuix.com/
http://hothardware.com/News/BOOM-Team-Fortress-2-Oculus-Rift-And-An-Omnidirectional-Treadmill-Equals-Big-Fun/