http://www.biolsci.org/v05p0706.htm
Highlights from the Paper:
Conclusions
"In conclusion, our data presented here strongly recommend that additional long-term (up to 2 years) animal feeding studies be performed in at least three species, preferably also multi-generational, to provide true scientifically valid data on the acute and chronic toxic effects of GM crops, feed and foods. Our analysis highlights that the kidneys and liver as particularly important on which to focus such research as there was a clear negative impact on the function of these organs in rats consuming GM maize varieties for just 90 days."
Causes Identified by the Study
"We investigated three different GM corn namely NK 603, MON 810 and MON 863, which were fed to rats for 90 days. The raw data have been obtained by European governments and made publically available for scrutiny and counter-evaluation. These studies constitute a model to investigate possible subchronic toxicological effects of these GM cereals in mammals and humans. These are the longest in vivo tests performed with mammals consuming these GMOs. The animals were monitored for numerous blood and organ parameters. One corn (NK 603) has been genetically engineered to tolerate the broad spectrum herbicide Roundup and thus contains residues of this formulation. The two other types of GM maize studied produce two different new insecticides namely modified versions of Cry1Ab (MON 810) and Cry3Bb1 (MON 863) Bacillus thuringiensis-derived proteins. Therefore, all these three GM maize contain novel pesticide residues that will be present in food and feed. As a result, the potential effects on physiological parameters, due either to the recognized mutagenic effects of the GM transformation process or to the presence of the above mentioned novel pesticides within these plants can be evaluated in animal feeding studies."